Auciello is directing basic and applied research programs on different fields, involving multi-component oxide thin films and application to systems and devices (ferroelectric memories, resistive change memories, nanoscale CMOS devices, photovoltaic energy generation / storage devices, high-frequency devices, piezoelectric thin films for MEMS/NEMS sensors and actuators); and nanocarbon thin films (ultrananocrystalline diamond (UNCD) and graphene films) and applications to industrial, electronics, MEMS/NEMS, and implantable medical devices). The UNCD film technology is now commercialized for industrial components and systems by Advanced Diamond Technologies (ADT), a Company founded by Auciello and Carlisle, spun-off from Argonne in 2003, and by Original Biomedical Implants (OBI), a company founded by Auciello and Gurman (MD), in 2013, for commercializing a new generation of UNCD-coated implantable medical devices.