Our research uses advanced imaging techniques to assess the interaction of neural activity and vascular physiology in healthy brains and neurological disease. This involves the design and implementation of tools to stimulate or monitor human physiology during MRI scanning, and the development of specialized MRI acquisition methods to characterize neurovascular function. In combination with bespoke signal processing pipelines developed in our lab, we aim to produce robust quantitative imaging biomarkers for studying Multiple Sclerosis, fatigue, migraine, stroke, dementia, spinal cord injury, and the response of individual patients to personalised therapeutic interventions. This work is in collaboration with Physical Therapy and Human Movement Sciences, Neurology, Radiology, the Center for Translational Imaging, and the Northwestern University Interdepartmental Neuroscience program.