There currently exists no standard methodology for tuning surface properties of implantable medical devices. To address this need, we have designed a technology that provides thin coatings that can be readily tuned for specific implant applications using non-toxic, non-solvent, aqueous based green chemistry. The thin coatings are to be applied toward implantable medical devices and biosensors, which is currently limited. The surface modifications that our technology allows will address unmet needs in bioadhesive coatings, blood contacting surfaces, and substrates that promote a living skin-like layer for cloaking of medical implants