His research interests include computational intelligence and machine learning in medical imaging, computer-aided detection and diagnosis, and medical image processing and analysis. He published more than 230 papers (including 95 peer-reviewed journal papers) and 75 refereed abstracts. His papers were cited more than 4,000 times by other researchers, and he has an h-index of 31. He is inventor on 30 patents (including 11 granted patents), which were licensed to several companies and commercialized. He published 9 books and 19 book chapters, and edited 6 journal special issues. He was awarded/co-awarded more than 44 grants including NIH R01 totaling 10.2 million dollars
